Real-Time Insight Into Cell Metabolism at Scale
Monitor DO, pH, OCR, and ECAR continuously—while simultaneously
cultivating cells in an optimized mixing and incubation environment.
At The Smallest Scale, For The Highest Throughput.
S.NEST® 2.0 is a culturing system that monitors cell metabolism in real-time and provides effective mixing in both 96 and 24-well plates. By integrating real-time monitoring, in-well mixing, and precise incubation control into a single instrument, S.NEST significantly reduces time and costs associated with cell culture R&D and manufacturing.
Simultaneously monitor oxygen, acidity, respiration, and glycolytic activity in every well.
Consistent suspension, higher oxygen transfer, and improved growth across 96/24-well plates.
Each with temperature, CO₂ control, humidity monitoring, and UV sterilization.
Run up to 96 wells per plate, 4 plates in parallel. Ideal for early-stage CLD, media optimization, and metabolic studies.
Strong correlation with shake flask culture for early clone ranking.
Format compatible with automated workflows and liquid handling integrations.
Streamlined Cell Line Development
Early-Stage Clone Selection
High-Throughput Drug Screening
Analysis of Cell Metabolism
Higher Viability For Primary Cultures
Miniaturized Model for Process Development
CHO Cells | HEK Cells | Hybridoma Cells | Stem Cells | Cancer Cells | iPSCs | PBMCs | T Cells | Spheroids | Organoids | E. Coli | Picha Pastorias
S.NEST monitors real time DO (dissolved oxygen) and pH in all wells using optical sensors in 96/24-well plates. The data is captured during the entire cell culture period. Our software can further calculate OCR (oxygen consumption rate) and ECAR (extracellular acidification rate) from this data, improving sensitivity to detect metabolic changes earlier.
See your cells thrive with our patented mixing technology – efficient pneumatic mixing in 96/24 well plates.
Tailor your culture conditions in each of the four independent incubation chambers equipped with precise temperature and CO₂ control, humidity monitoring, water reservoir, and UV sterilization. Cultivate flexibly and precisely with independent mixing control for each chamber, allowing parallel execution of both mixing and static culture.
Designed for maximum productivity, S.NEST is automation-friendly, saving you both time and labor. Its seamless integration with your robotic arm, along with SiLA 2.0 compatibility, makes it a versatile solution. Build your automated station for a streamlined workflow.
Book a demo now to witness the transformative power of S.NEST® 2.0 in action. Accelerate your cell line development, streamline your processes, and unlock new possibilities in cell culture research.
